In the year 1752 Joshua and Naomi Collins, with young son Barnabas, set sail from Liverpool, England, to start a new life in America. But even an ocean was not enough to escape the mysterious curse that has plagued their family. Two decades pass, and Barnabas (Johnny Depp) has the world at his feet — or at least the town of Collinsport, Maine. The master of Collinwood Manor, Barnabas is rich, powerful and an inveterate playboy…until he makes the grave mistake of breaking the heart of Angelique Brouchard (Eva Green). A witch, in every sense of the word, Angelique dooms him to a fate worse than death: turning him into a vampire and then burying him alive.