Homicidal sociopath trucker Rusty Nail makes his return in Road Kill 2, as four teenagers Kayla, Melissa, Bobby and Nik embark on a road trip to Las Vegas. Disaster strikes when their car suddenly breaks down, they find themselves stranded in the sweltering desert and make the fatal error of stealing a car belonging to the depraved and sadistic Rusty Nail. With an insatiable penchant for punishment and brutality, Rusty terrorizes the group in a series of disturbing and deadly encounters, forcing them to play a series of incessantly ruthless mind games that inevitably lead to their torture and face death straight-on in the eye.