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In a totalitarian society in a near future, the undercover detective Bob Arctor is working with a small time group of drug users trying to reach the big distributors of a brain-damaging drug called Substance D. His assignment is promoted by the recovery center New Path Corporation, and when Bob begins to lose his own identity and have schizophrenic behavior, he is submitted to tests to check his mental conditions.

Genre(s) : [Animation

Actors :
Rory Cochrane Charles Freck
Robert Downey Jr James Barris
Mitch Baker Brown Bear Lodge Host
Keanu Reeves Bob Arctor
Sean Allen Additional Fred Scramble Suit Voice (voice)
Cliff Haby Voice from Headquarters (voice)
Steven Chester Prince Cop
Winona Ryder Donna Hawthorne
Natasha Janina Valdez Waitress (as Natasha Valdez)
Mark Turner Additional Hank Scramble Suit Voice (voice)
Woody Harrelson Ernie Luckman
Chamblee Ferguson Medical Deputy #2
Angela Rawna Medical Deputy #1
Eliza Stevens Arctor's Daughter #1
Sarah Menchaca Arctor's Daughter #2
Melody Chase Arctor's Wife
Leif Anders Freck Suicide Narrator (voice)
Turk Pipkin Creature
Alex Jones Street Prophet
Lisa Marie Newmyer Connie
Wilbur Penn Medical Officer #1
Ken Webster Medical Officer #2
Hugo Perez New Path Staff Member #1
Rommel Sulit New Path Staff Member #2
Dameon Clarke Mike
Christopher Ryan New Path Resident #1
Leila Plummer New Path Resident #2
Jason Douglas New Path Farm Manager
Marco Perella Donald
Joe Basquez Undercover Cop (uncredited)
Jonathan Cacy Brown Bear Lodge Member (uncredited)
Jack Cruz Police Officer (uncredited)
Gary Teague Brown Bear Lodge Member (uncredited)