The government sets up a Zombie squad after an epidemic has made the world run rampant with living corpses. Raimi, Mercer, Kuller, and others head off to Ohio to try and find a cure to the epidemic but soon run into a crazy cult of zombie lovers who are set on preserving the zombies and letting a new world be born because they believe that it's God's will. When Mercer gets infected with the zombie virus, Raimi and the others must work quickly to find a cure and avoid the cult.